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Vaccine Weekly

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DNA Vaccines



Studies conducted at Peking University on DNA vaccines recently published



June 17th, 2009

"We evaluated the immunogenicity and protective efficacy of a combined DNA vaccine containing six genes encoding immunodominant antigens from Mycobacterium bovis and Brucella abortus. The number of lymph node and spleen cultures positive for M. bovis and B. abortus from calves immunized with the combined DNA vaccine was significantly reduced (p < 0.01) compared with unvaccinated calves after challenge with virulent M. bovis and B. abortus 544," scientists in Beijing, People's Republic of China report.

"The combined DNA vaccine group displayed stronger antigen-specific interferon-gamma (IFN-gamma) responses and antigen-specific IFN-gamma ELISPOT activities 2 months...


Source: Vaccine Weekly (2009-06-17)

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