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Immunization
Data on immunization described by researchers at University of Nebraska
June 17th, 2009
New research, 'Impairment of D-alanine biosynthesis in Mycobacterium smegmatis determines decreased intracellular survival in human macrophages,' is the subject of a report. "d-Alanine is a structural component of mycobacterial peptidoglycan. The primary route of d-alanine biosynthesis in eubacteria is the enantiomeric conversion from l-alanine, a reaction catalysed by d-alanine racemase (Alr). Mycobacterium smegmatis alr insertion mutants are not dependent on d-alanine for growth and display a metabolic pattern consistent with an alternative pathway for d-alanine biosynthesis," scientists in the United States report. "In this study, we demonstrate that the M....
Source: Vaccine Weekly (2009-06-17)
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