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Vaccine Weekly

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Allergies



Researchers from National Institute of Allergy and Infectious Diseases publish findings in allergies



June 17th, 2009

"Despite the longstanding appreciation of communication between the nervous and the immune systems, the nature and significance of these interactions to immunity remain enigmatic. Here, we show that 6-hydroxydopamine-mediated ablation of the mouse peripheral sympathetic nervous system increases primary CD8(+) T cell responses to viral and cellular antigens presented by direct priming or cross-priming," researchers in the United States report.

"The sympathetic nervous system also suppresses antiviral CD4(+) T cell responses, but this is not required for suppressing CD8(+) T cell responses. Adoptive transfer experiments indicate that enhanced CD8(+) responses do not...


Source: Vaccine Weekly (2009-06-17)

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