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Vaccine Weekly

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Chagas Disease



New Chagas disease study findings have been reported by scientists at Federal University



June 17th, 2009

According to a study from Ouro Preto, Brazil, "The protozoan Trypanosoma cruzi is the causative agent of Chagas disease. There are no vaccines or effective treatment, especially in the chronic phase when most patients are diagnosed."

"There is a clear necessity to develop new drugs and strategies for the control and treatment of Chagas disease. Recent papers have suggested the ecto-nucleotidases (from CD39 family) from pathogenic agents as important virulence factors. In this study we evaluated the influence of Ecto-Nucleoside-Triphosphate-Diphosphohydrolase (Ecto-NTPDase) activity on infectivity and virulence of T. cruzi using both in vivo and in vitro models. We...


Source: Vaccine Weekly (2009-06-17)

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