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Studies from Albany Medical College, Medical College yield new data on vaccines

Published in Vaccine Weekly, June 17th, 2009

"Francisella tularensis is a category A biothreat agent for which there is no approved vaccine and the correlates of protection are not well understood. In particular, the relationship between the humoral and cellular immune response to F. tularensis and the relative importance of each in protection is controversial," investigators in the United States report.

"Yet, understanding this relationship will be crucial to the development of an effective vaccine against this organism. We demonstrate, for the first time, a differential requirement for Immoral vs cellular immunity in vaccine-induced protection against F. tularensis infection, and that the requirement for Ab...

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