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Vaccines
Researchers from University of Insubria discuss findings in vaccines
June 17th, 2009
New investigation results, 'Irradiated CIITA-positive mammary adenocarcinoma cells act as a potent anti-tumor-preventive vaccine by inducing tumor-specific CD4+ T cell priming and CD8+ T cell effector functions,' are detailed in a study published in International Immunology. "In the present study, we investigated the possibility to use irradiated, non-replicating class II transcriptional activator (CIITA)-transfected tumor TS/A cells as a cell-based vaccine. Eighty-three percent of TS/A-CIITA-vaccinated mice were completely protected from tumor growth and the remaining 17% displayed significant reduction of tumor growth," investigators in Varese, Italy report. ...
Source: Vaccine Weekly (2009-06-17)
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