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Cancer Vaccines
Data on cancer vaccines published by researchers at National Cancer Institute
June 24th, 2009
"The tumor-associated Tn antigen has been investigated extensively as a biomarker and therapeutic target. Cancer vaccines containing the Tin antigen as a single tumor antigen or as a component of a polyvalent vaccine have progressed into phase I and II clinical trials," scientists in the United States report. "One major focus of Tn-based vaccines is the treatment of prostate cancer patients. Although expression of the antigen on prostate tumors is a critical prerequisite, previous reports investigating Tn expression in prostate tumors have produced conflicting results. Using a combination of immunohistochemistry and carbohydrate microarray profiling, we show that only...
Source: Vaccine Weekly (2009-06-24)
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