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Vaccine Weekly

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Immunization



Research from University of Wisconsin yields new findings on immunization



July 1st, 2009

According to a study from the United States, "Heart failure (HF) patients are at risk for influenza despite widespread vaccination. Both humoral (antibody) and cytotoxic T-lymphocyte (CTL) responses are important for protection."

"We explored antibody- and CTL-mediated responses to the influenza vaccine in HF patients compared with healthy controls. We studied 29 HF patients (9 ischemic, 20 nonischemic) stable on HF therapies and 17 healthy controls. Participants had phlebotomy before and after influenza vaccination. Antibody production was measured in serum by hemagglutination inhibition assay and CTL responses (via interferon [IFN]-gamma and interleukin [IL]-10...


Source: Vaccine Weekly (2009-07-01)

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