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Immunization
Study findings from Karolinska Institute broaden understanding of immunization
July 1st, 2009
Scientists discuss in 'Vaccination with beta(2)-microglobulin-deficient dendritic cells protects against growth of beta(2)-microglobulin-deficient tumours' new findings in immunization. "Defects in cell surface expression of major histocompatibility complex class I antigen molecules are common in tumor cells. We have previously described the generation of adaptive immunity to tumor cells deficient in the transporter associated with antigen processing molecule," investigators in Stockholm, Sweden report. "In this study, we demonstrate enhanced in vivo protection against growth of beta(2)-microglobulin-deficient tumor cells in syngeneic C57Bl/6 mice, following vaccination...
Source: Vaccine Weekly (2009-07-01)
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