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Immunotherapy
Investigators at Tokyo Metropolitan Institute of Medical Science zero in on immunotherapy
July 1st, 2009
A report, 'Development of transgenic rice expressing mite antigen for a new concept of immunotherapy,' is newly published data in International Archives of Allergy and Immunology. "To elucidate the usefulness of antigen-specific immunotherapy based on oral vaccination with an edible part of the plant, we examined the effect of transgenic (Tg) rice seeds expressing an immunodominant fragment of the group 1 antigen of Dermatophagoides pteronyssinus (Der p 1) on a murine model of asthma. Mice were orally vaccinated with the Tg or non-Tg rice seeds for 2 weeks, then they were immunized with recombinant Der p 1 (rDer p 1) and alum intraperitoneally," scientists writing in the journal...
Source: Vaccine Weekly (2009-07-01)
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