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Cancer Vaccines
Research from N.Y. Shih et al has provided new information about cancer vaccines
July 1st, 2009
"Macrophage inflammation protein-3 alpha (MIP-3 alpha) is a chemokine expressed in inflamed tissue and capable of inducing migration of immature dendritic cells (DCs) or Langerhans cells. We Postulated that conditioning vaccination sites with MIP-3 alpha might enhance the efficacy of subsequently administered DC-based cancer vaccines," scientists in Tainan, Taiwan report. "Our results demonstrate that subcutaneously injection of irradiated tumor cells expressing MIP-3 alpha induces Substantial cell infiltration to the injection site. Vaccination of irradiated turner cells expressing MIP-3 alpha. followed by DCs pulsed with irradiated tumor cells can effectively suppress...
Source: Vaccine Weekly (2009-07-01)
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