Vaccine Weekly
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Drug Resistance
Findings in drug resistance reported from University of Oxford
July 1st, 2009
According to recent research from Vietnam, "Clostridium tetani is the etiologic agent of the muscle-spasming disease tetanus. Despite all effective vaccine, tetanus is all ongoing problem in some developing countries." "Diagnosis by bacterial culture is not done because it is generally unnecessary and the entry of route of the bacteria can be inapparent. We attempted to isolate and evaluate C. tetani from the wounds of 84 patients with tetanus. We effectively isolated C tetani from 45 patients. All strains tested positive by polymerase chain reaction for the gene encoding tetanus neurotoxin. Antimicrobial susceptibilities were determined by disc diffusion and E-test....
Source: Vaccine Weekly (2009-07-01)
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