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Flu Vaccines
New flu vaccines data have been reported by Y. Takahashi and co-authors
July 1st, 2009
According to a study from Tokyo, Japan, "Hemagglutination-inhibition (HI) antibody titers correlate with protective immunity to seasonal influenza viruses. However, inactivated H5N1 influenza vaccines from Vietnam 2004 strains afford protection without producing high or even detectable HI antibodies." "BALB/c mice were immunized twice (at a 3-week interval) with inactivated whole-virus influenza vaccine produced using reverse genetics, with the internal genes of A/PR/8/34 (a high-yield strain) and the hemagglutinin (HA) and neuraminidase (NA) genes of A/Vietnam/1194/04 (H5N1) virus (NIBRG-14) adjuvanted with alum (5 mu g of HA). Either HA- or NA-binding antibodies were...
Source: Vaccine Weekly (2009-07-01)
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