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HIV/AIDS
Research from University of Oxford provides new data on HIV/AIDS
July 1st, 2009
According to recent research from Oxford, the United Kingdom, "Induction of a long-term immunological memory, which can expand and defend the host upon pathogen encounter, is the ''holy grail'' of vaccinology. Here, using a sensitive cultured IFN-gamma ELISPOT assay, we show that 50% (15 out of 30) of healthy, HIV-1/2-uninfected volunteers who received pTHr.HIVA DNA prime-modified vaccinia virus Ankara." "HIVA boost vaccine regimen 1 to 3 1/2 years ago had detectable HIV-1-specific T-cell responses. These T cells, predominantly of the CD4(+) subtype, could proliferate and produce multiple cytokines in response to in vitro peptide stimulation. Peptide mapping studies...
Source: Vaccine Weekly (2009-07-01)
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