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Vaccines
New vaccines research reported from Nottingham Trent University
July 1st, 2009
Current study results from the report, 'CTL responses to Leishmania mexicana gp63-cDNA vaccine in a murine model,' have been published. According to a study from Clifton, the United Kingdom, "Immunity to Leishmania is believed to be strongly dependent upon the activation of Th1 immune responses, although the exact role of cytotoxic T lymphocytes (CTLs) has not yet been determined. The aims of this study were to establish a suitable cytotoxicity assay to measure CTL activity and to compare immunity induced by Leishmania mexicana gp63 cDNA via i.m. injection and gene gun immunization in the BALB/c mouse model." "The CTL activity was evaluated by short-term (51)Cr-release...
Source: Vaccine Weekly (2009-07-01)
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