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Vaccine Weekly

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Vaccines



Data from Health Protection Agency provide new insights into vaccines



July 8th, 2009

New research, 'Bivalent recombinant vaccine for botulinum neurotoxin types A and B based on a polypeptide comprising their effector and translocation domains that is protective against the predominant A and B subtypes,' is the subject of a report. "The botulinum neurotoxins (BoNTs) are a large family of extremely potent, neuroparalytic, dichain proteins which act at the peripheral nervous system. The wide genetic diversity observed with this neurotoxin family poses a significant challenge for the development of an effective botulinum vaccine," investigators in Salisbury, the United Kingdom report.

"The present study describes a vaccine development platform based on...


Source: Vaccine Weekly (2009-07-08)

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