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Cancer Vaccines
New findings reported from J. Rossowska and co-authors describe advances in cancer vaccines
July 8th, 2009
"The use of dendritic cells (DCs) loaded with tumour antigen is one of the most promising approaches to induce tumour-specific immune response. However. methods of the vaccine preparation have not yet been standardized. The purpose of the study was to analyse the anti-tumour efficacy 017 tumour antigen-loaded mouse bone marrow-derived dendritic cells (BM-DC/TAg) at different maturation stages," investigators in Wroclaw, Poland report. "BM-DCs were loaded with MC38 colon carcinoma cell lysate (TAg) alone, to become partially differentiated, or were additionally stimulated with inflammatory cytokines Such LIS TNF-alpha, IFN-gamma, or IL-12 to reach complete maturity....
Source: Vaccine Weekly (2009-07-08)
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