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Foot and Mouth Disease
Research from M. Hema and co-researchers yields new findings on foot and mouth disease
July 8th, 2009
According to recent research from Hyderabad, India, "Foot-and-mouth disease virus (FMDV) serotype 0 is the most predominant among the endemic serotypes in India. A stable, full-length cDNA clone of FMDV type O1BFS 1860 preceded by a bacteriophage T7 polymerase promoter was assembled in a plasmid vector pGEM(R)-7Zf(-)." "An similar to 8.2 kb PCR product was amplified from the cDNA clone and a full-length RNA was generated from it by in vitro transcription. Transfection of BHK-21 cells with the in vitro transcripts resulted in the production of infectious recombinant FMDV particles as evidenced by cytopathic effects (CPE). Further, characterization of the recombinant...
Source: Vaccine Weekly (2009-07-08)
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