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Vaccine Weekly

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HIV/AIDS



New HIV/AIDS data have been reported by researchers at Harvard University



July 8th, 2009

"The interferon (IFN)-gamma Elispot assay has been widely used as a general screening method for the quantification and characterization of the human immunodeficiency virus (HIV)-specific CD8+ T cell responses. However, the predictive power of this assay has been challenged due to the lack of efficacy of a recently conducted HIV vaccine phase IIb trial, despite induction of robust Elispot responses," scientists writing in the journal Nature Protocols report.

"This finding plus improvements in multiparameter flow cytometry, which has the potential advantage of simultaneously quantifying numerous parameters, raises questions regarding the future role of IFN-gamma...


Source: Vaccine Weekly (2009-07-08)

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