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Vaccine Weekly

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Life Sciences



Studies from S.C. Sutradhar et al provide new data on life sciences



July 8th, 2009

"Zostavax has been shown to be efficacious in the prevention of herpes zoster and generally well tolerated in clinical trials among subjects 60 years old or older. This prespecified combined analysis from two studies compares the levels of immunogenicity and safety of Zostavax in subjects 50 to 59 years old versus those in subjects >= 60 years old," researchers in the United States report.

"Varicella-zoster virus (VZV) antibody (Ab) titers were measured by glycoprotein enzyme-linked immunosorbent assay at baseline and 4 weeks postvaccination. Noninferiority was evaluated by estimated geometric mean severalfold rise (GMFR) ratio (50 to 59 years old/ >= 60 years...


Source: Vaccine Weekly (2009-07-08)

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