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Chronic Obstructive Pulmonary Disease



Findings from E.R. Lafontaine and co-authors broaden understanding of chronic obstructive pulmonary disease



July 8th, 2009

According to recent research published in the journal Clinical and Vaccine Immunology, "Moraxella catarrhalis is a common cause of respiratory tract infection in the setting of chronic obstructive pulmonary disease (COPD). Adults with COPD acquire and clear strains of M. catarrhalis from the respiratory tract continuously and develop strain-specific protection following clearance of a strain."

"In previous work, we identified Hag/MID (Moraxella immunoglobulin D-binding protein), a large multifunctional surface protein that acts as an adhesin and hemagglutinin, as a target of antibody responses in adults with COPD after clearance of M. catarrhalis. The goal of the...


Source: Vaccine Weekly (2009-07-08)

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