Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Haemophilus Vaccines
New haemophilus vaccines data have been reported by scientists at University of North Carolina, Division of Infectious Diseases
July 8th, 2009
Scientists discuss in 'An immunogenic, surface-exposed domain of Haemophilus ducreyi outer membrane protein HgbA is involved in hemoglobin binding' new findings in haemophilus. According to recent research published in the journal Infection and Immunity, "HgbA is the sole TonB-dependent receptor for hemoglobin (Hb) acquisition of Haemophilus ducreyi. Binding of Hb to HgbA is the initial step in heme acquisition from Hb." "To better understand this step, we mutagenized hgbA by deletion of each of the 11 putative surface-exposed loops and expressed each of the mutant proteins in trans in host strain H. ducreyi FX547 hgbA. All mutant proteins were expressed,...
Source: Vaccine Weekly (2009-07-08)
|
