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Reports on vaccines findings from Tsinghua University provide new insights

Published in Vaccine Weekly, July 15th, 2009

"Classical swine fever is a highly contagious viral disease for which many researchers are endeavoring to develop safe and efficient vaccines. An amino acid sequence, TAVSPTTLR, residing in glycoprotein E2, was identified as a highly conserved neutralizing epitope," scientists writing in the journal Viral Immunology report.

"This epitope was demonstrated to have the capacity of inducing neutralizing antibodies, and the sequences flanking it may contribute to the production of functional humoral immune responses. One interesting question is whether such a structural contribution can be compensated for. In this report, we designed and produced several chimeric...

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