Vaccines

New findings from University of Pennsylvania, Medical Department describe advances in vaccines

Published in Vaccine Weekly, July 22nd, 2009

According to recent research from the United States, "Improving the potency of immune responses is paramount among issues concerning vaccines against deadly pathogens. IL-28B belongs to the newly described interferon lambda (IFN lambda) family of cytokines, and has not yet been assessed for its potential ability to influence adaptive immune responses or act as a vaccine adjuvant."

"We compared the ability of plasmid-encoded IL-28B to boost immune responses to a multiclade con-sensus HIV Gag plasmid during DNA vaccination with that of IL-12. We show here that IL-28B, like IL-12, is capable of robustly enhancing adaptive immunity. Moreover, we describe for the first time...

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Source: Vaccine Weekly (2009-07-22)

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