Falciparum Malaria
Report summarizes falciparum malaria study findings from A. Jalloh and co-researchers
Published in Vaccine Weekly, August 12th, 2009
"In the context of the development of a successful malaria vaccine, understanding the polymorphisms exhibited by malaria antigens in natural parasite populations is crucial for proper vaccine design. Recent observations have indicated that sequence polymorphisms in the C-terminal T-cell epitopes of the Plasmodium falciparum circumsporozoite protein (Pfcsp) are rather low and apparently stable in low endemic areas," scientists in Tochigi, Japan report.
"This study sought to assess the pattern in a malaria endemic setting in Africa, using samples from Freetown, Sierra Leone. Filter-paper blood samples were collected from subjects at a teaching hospital in Freetown during...
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Source: Vaccine Weekly (2009-08-12)
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