Life Sciences
Research reports from Johnson & Johnson provide new insights into life sciences
Published in Vaccine Weekly, September 23rd, 2009
"The innate immune system of mammals is a key defense mechanism against invading foreign pathogens. Innate immune stimulants may have applications as vaccine adjuvants as well as in the treatment of cancer and some viral diseases, and clinical studies have been performed using agonists of Toll-like receptors (TLRs) 7, 8, and 9. The high-throughput screens for such agonists have typically relied on the overexpression of a single TLR gene in an immortalized cell line and are inherently artificial systems that are restricted to the identification of agonists for a single receptor," scientists in Australia report.
"The authors describe 2 assays for the identification of...
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Source: Vaccine Weekly (2009-09-23)
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