Published in Vaccine Weekly, October 21st, 2009
"By the use of reverse genetics and dual promoters, we constructed a 23.6-kb eight-unit plasmid that contains all the required constituents to generate influenza virus in chicken cells. Our ''one-plasmid'' system generated higher titers of influenza virus in chicken cells than the ''eight-plasmid'' system, enabling a simpler approach for generating vaccine seeds," wrote...
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