Studies from Wadsworth Center, New York State Department of Health have provided new data on anthrax vaccines

Current study results from the report, 'Neutralizing monoclonal antibodies directed against defined linear epitopes on domain 4 of anthrax protective antigen,' have been published. "The anthrax protective antigen (PA) is the receptor-binding subunit common to lethal toxin (LT) and edema toxin (ET), which are responsible for the high mortality rates associated with inhalational Bacillus anthracis infection. Although recombinant PA (rPA) is likely to be an important constituent of any future anthrax vaccine, evaluation of the efficacies of the various candidate rPA vaccines is currently difficult, because the specific B-cell epitopes involved in toxin neutralization have not been...

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