University of Pittsburgh Schools of the Health Sciences

Pitt, US Army team designs new strategy to find drugs to treat neglected infection

Published in Vaccine Weekly, November 18th, 2009

Using an unconventional approach that they designed, University of Pittsburgh drug discoverers and their collaborators at Walter Reed Army Institute of Research have identified compounds that hold promise for treating leishmaniasis, a parasitic infection that many consider one of the world's most overlooked diseases. The findings are available online today in PLoS Neglected Tropical Diseases.

These drug candidates, which are able to disrupt the growth of a certain stage in the life cycle of the parasite, were found by screening nearly 200,000 chemical compounds and then regrouping them into chemotypes or chemical classes, both new and known, explained senior...

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Source: Vaccine Weekly (2009-11-18)

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