Yale University

New synthetic molecules trigger immune response to HIV and prostate cancer

Published in Vaccine Weekly, December 2nd, 2009

Researchers at Yale University have developed synthetic molecules capable of enhancing the body's immune response to HIV and HIV-infected cells, as well as to prostate cancer cells. Their findings, published online in the Journal of the American Chemical Society, could lead to novel therapeutic approaches for these diseases.

The molecules - called "antibody-recruiting molecule targeting HIV" (ARM-H) and "antibody-recruiting molecule targeting prostate cancer" (ARM-P) - work by binding simultaneously to an antibody already present in the bloodstream and to proteins on HIV, HIV-infected cells and cancer cells. By coating these pathogens in antibodies, the molecules flag...

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Source: Vaccine Weekly (2009-12-02)

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