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Alzheimer Disease

Data from University of California advance knowledge in Alzheimer disease

Published in Vaccine Weekly, December 16th, 2009

"Alzheimer's disease (AD) is pathologically characterized by accumulation of beta-amyloid (A beta) protein deposits and/or neurofibriffary tangles in association with progressive cognitive deficits. Although numerous studies have demonstrated a relationship between brain pathology and AD progression, the Alzheimer's pathological hallmarks have not been found in the AD retina," researchers in the United States report.

"A recent report showed A beta plaques in the retinas of APPswe/PS1 Delta E9 transgenic mice. We now report the detection of A beta plaques with increased retinal microvascular deposition of A beta and neuroinflammation in Tg2576 mouse retinas. The majority...

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