Malaria Vaccines
Study findings from University Hospital broaden understanding of malaria vaccines
Published in Vaccine Weekly, December 16th, 2009
Scientists discuss in 'Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated Plasmodium falciparum protein PFF0165c' new findings in malaria. "We have identified new malaria vaccine candidates through the combination of bioinformatics prediction of stable protein domains in the Plasmodium falciparum genome, chemical synthesis of polypeptides, in vitro biological functional assays, and association of an antigen-specific antibody response with protection against clinical malaria. Within the predicted open reading frame of P. falciparum hypothetical protein PFF0165c, several segments with low hydrophobic amino acid content, which...
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Source: Vaccine Weekly (2009-12-16)
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