Vaccines
New findings in vaccines described from University of Michigan, Department of Internal Medicine
Published in Vaccine Weekly, December 16th, 2009
Current study results from the report, 'A heterologous helper T-cell epitope enhances the immunogenicity of a multiple-antigenic-peptide vaccine targeting the cryptic loop-neutralizing determinant of Bacillus anthracis protective antigen,' have been published. "We previously showed that a multiple antigenic peptide (MAP) displaying amino acids (aa) 305 to 319 from the 2beta2-2beta3 loop of protective antigen (PA) can elicit high-titered antibody that neutralizes lethal toxin (LeTx) in vitro and that this loop-neutralizing determinant (LND) specificity is absent in PA-immune rabbits. Some immune rabbits were, however, nonresponders to the MAP," scientists in the United States report.
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Source: Vaccine Weekly (2009-12-16)
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