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Cancer Vaccines

University of Kentucky, Medical Department publishes research in cancer vaccines

Published in Vaccine Weekly, January 6th, 2010

According to a study from the United States, "The Current study characterized peripheral blood mononuclear cells (PBMC) obtained from leukapheresis products of patients with non-small cell lung cancer (NSCLC) for cytokine release, the ability to incorporate tritiated thymidine following stimulation using PHA as well as the levels of both CD4 and CD8 regulatory T cells (Tregs) as defined by FoxP3 expression. were compared to normal donor PBMC obtained from buffy coat products."

"Heterogeneous levels of Th1 (gamma interferon and IL-2), Th2 (IL-10 and IL-13), pro-inflammatory (TNF-alpha and IL-6) and the hematopoietic inducing cytokine GMCSF were detected from both...

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