Dentistry
Data on dentistry described by researchers at Wuhan University
Published in Vaccine Weekly, January 20th, 2010
In this recent report published in the journal Acta Pharmacologica Sinica, researchers in Wuhan, People's Republic of China conducted a study "To prepare a clinical-grade anti-caries DNA vaccine pGJA-P/VAX and explore its immune effect and protective efficacy against a cariogenic bacterial challenge. A large-scale industrial production process was developed under Good Manufacturing Practices (GMP) by combining and optimizing common unit operations such as alkaline lysis, precipitation, endotoxin removal and column chromatography."
"Quality controls of the purified bulk and final lyophilized vaccine were conducted according to authoritative guidelines. Mice and...
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Source: Vaccine Weekly (2010-01-20)
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