Allergies
Research results from S.A. Beckham and co-authors update knowledge of allergies
Published in Vaccine Weekly, January 27th, 2010
According to a study from Brisbane, Australia, "The scabies mite, Sarcoptes scabiei var. hominis, infests human skin, causing allergic reactions and facilitating bacterial infection by Streptococcus sp., with serious consequences such as rheumatic fever and rheumatic heart disease. To identify a possible drug target or vaccine candidate protein, we searched for homologues of the group 3 allergen of house dust mites, which we subsequently identified in a cDNA library."
"The native protein, designated Sar s 3, was shown to be present in the mite gut and excreted in fecal pellets into mite burrows within the upper epidermis. The substrate specificity of proteolytically...
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Source: Vaccine Weekly (2010-01-27)
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