Leptospirosis

New leptospirosis study results reported from A.D. Chagasjunior et al

Published in Vaccine Weekly, January 27th, 2010

"In determining the efficacy of new vaccine candidates for leptospirosis, the primary end point is death and an important secondary end point is sterilizing immunity. However, evaluation of this end point is often hampered by the time-consuming demands and complexity of methods such as culture isolation (CI)," scientists in Salvador, Brazil report.

"In this study, we evaluated the use of an imprint (or touch preparation) method (IM) in detecting the presence of leptospires in tissues of hamsters infected with Leptospira interrogans serovar Copenhageni. In a dissemination study, compared to Cl, the IM led to equal or improved detection of leptospires in kidney, liver,...

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Source: Vaccine Weekly (2010-01-27)

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