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Immunization

Studies from P. Castro and colleagues yield new information about immunization

Published in Vaccine Weekly, February 10th, 2010

"Vaccination is recommended for HIV-infected patients. Transient increases of viral load (VL) and risk of developing resistance to HAART have been described," researchers in Barcelona, Spain report.

"In addition, VL rebounds could increase HIV-specific immune responses. Twenty-six successfully treated HIV-infected adults were randomized to receive a vaccination schedule or placebo during 12 months. Afterward, HAART was discontinued. Influences of vaccination over VL, genotypic mutations, different T cell subsets, and HIV-1-specific immune responses were evaluated. did not present any secondary effect. No differences in incidence of detectable VL determinations were...

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