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Bird Flu

Study findings from Pohang University of Science & Technology provide new insights into bird flu

Published in Vaccine Weekly, February 10th, 2010

According to recent research from South Korea, "Development of effective vaccines against highly pathogenic avian influenza (HPAI) H5N1 viruses is a global public health priority."

"Considering the difficulty in predicting HPAI H5N1 pandemic strains, one strategy used in their design includes the development of formulations with the capacity of eliciting broad cross-protective immunity against multiple viral antigens. To this end we constructed a replication-defective recombinant adenovirus-based avian influenza virus vaccine (rAdv-AI) expressing the codon-optimized M2eX-HA-hCD40L and the M1-M2 fusion genes from HPAI H5N1 human isolate. Although there were no...

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