Flu Vaccines

Data on flu vaccines published by A. Naskalska and colleagues

Published in Vaccine Weekly, February 10th, 2010

According to recent research published in the journal Vaccine, "We propose a novel influenza vaccine composed of the adenovirus dodecahedron (Dd) as delivery platform carrying an internal influenza matrix protein M1. To attach the antigen to the vector we used WW domains interacting with Dd."

"Successful internalization of the Dd-M1WW complex was observed using biochemical and cell biology techniques. We show here that the complex of Dd with antigen is a potent activator of human myeloid dendritic cells (MDC), and that it is efficiently presented by MDC to M1-specific CD8+ T lymphocytes," wrote A. Naskalska and colleagues.

The researchers...

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Source: Vaccine Weekly (2010-02-10)

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