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Tuberculosis Vaccines

Research from Karolinska Institut in tuberculosis vaccines provides new insights

Published in Vaccine Weekly, February 24th, 2010

A report, 'Peptide microarray-based identification of Mycobacterium tuberculosis epitope binding to HLA-DRB1*0101, DRB1*1501, and DRB1*0401,' is newly published data in Clinical and Vaccine Immunology. According to recent research from Sweden, "A more effective vaccine against Mycobacterium tuberculosis is needed, and a number of M. tuberculosis vaccine candidates are currently in preclinical or clinical phase I and II studies. One of the strategies to select M. tuberculosis (protein) targets to elicit a CD8(+) or CD4(+) T-cell response is to gauge the binding of candidate peptides to major histocompatibility complex (MHC) class I or class II molecules, a...

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