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Immunization

Research on immunization described by scientists at China Agricultural University, College of Biological Science

Published in Vaccine Weekly, March 3rd, 2010

New research, 'FK506 as an adjuvant of tolerogenic DNA vaccination for the prevention of experimental autoimmune encephalomyelitis,' is the subject of a report. "DNA vaccination is a strategy that has been developed primarily to elicit protective immunity against infection and cancer. DNA vaccine was used, in conjunction with an immunosuppressant, to tolerize harmful autoimmunity," researchers in Beijing, People's Republic of China report.

"Immunization of C57BL/6 mice with MOG(35-55), a myelin oligodendrocyte glycoprotein-derived peptide, and FK506 (Tacrolimus) as a tolerogenic adjuvant stimulated regulatory dendritic cells, induced antigen-specific regulatory T cells...

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