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Pneumocystis

Studies conducted at Nantong University, Medical Department on pneumocystis recently published

Published in Vaccine Weekly, March 10th, 2010

According to recent research from Nantong, People's Republic of China, "Pneumocystis is an opportunistic pathogen that often causes fatal pneumonia in immunocompromised patients. It remains an important cause of morbidity and mortality in immunocompromised hosts."

"Therefore, the development of a vaccine is needed. Kexin is a furin-like protease which may be involved in the proteolytic processing of other proteins of Pneumocystis. We focused on the cellular and humoral responses to the kexin antigen fragment of Pneumocystis in our study. The full-length DNA sequence of the kexin gene was amplified from rat Pneumocystis carinii (P. carinii). The recombinant plasmid...

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