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Cancer Vaccines

Investigators at University Medical Center publish new data on cancer vaccines

Published in Vaccine Weekly, March 24th, 2010

Fresh data on cancer are presented in the report 'Construction of a triple modified p53 containing DNA vaccine to enhance processing and presentation of the p53 antigen.' According to a study from Netherlands, "More effective and less toxic treatments are urgently needed in the treatment of patients with cancer. The tumor suppressor protein p53 is a tumour-associated antigen that could serve that purpose when applied in an immunologic approval to cancer."

"It is mutated in approximately 50% of the tumours resulting in p53 overexpression, which can serve as target for therapy. To improve the immunisation results in patients with p53 overexpression tumours we constructed...

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