Researchers detail in 'Novel CCR5 antagonists for the treatment of HIV infection: a review of compounds patented in 2006 - 2008,' new data in HIV/AIDSvaccine. "IMPORTANCE OF THE FIELD: The HIV/AIDS epidemic and the resultant therapeutic efforts have continued to evolve over the last several years. The continued challenges in vaccine development, the growing longevity of the patient population and the emergence of resistant strains to current highly active antiretroviral therapy necessitate the development of new, effective therapeutics which target novel mechanism of actions," scientists in the United States report.
"CCR5, a member of the GPCR superfamily, plays a key...
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