Life Sciences
Researchers at Center of Infection publish new data on life sciences
Published in Vaccine Weekly, March 31st, 2010
Fresh data on life sciences are presented in the report 'The member of the cyclic di-nucleotide family bis-(3', 5')-cyclic dimeric inosine monophosphate exerts potent activity as mucosal adjuvant.' According to a study from Braunschweig, Germany, "Here we demonstrated that bis-(3',5')-cyclic dimeric inosine monophosphate (c-di-IMP) exhibits potent adjuvant properties. BALB/c or C57BL/6 mice were immunized with the model antigens beta-galactosidase (beta-Gal) or Ovalbumin (OVA) alone or co-administered with c-di-IMP by the intranasal route."
"Animals receiving c-di-IMP showed significantly higher anti-beta-Gal or OVA immunoglobulin G titres (IgG) in sera than those...
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Source: Vaccine Weekly (2010-03-31)
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