Human Papillomavirus
Findings from Chulalongkorn University, Medical Department provide new insights into human papillomavirus
Published in Vaccine Weekly, May 5th, 2010
According to a study from Bangkok, Thailand, "The aim of this study was to attain molecular knowledge of human papillomavirus type 18 (HPV18) by sequencing the whole genome of HPV18 isolated from Thai women at various clinical stages of disease progression. Our group analyzed 9 samples of whole-genome HPV18 in infected women ranging from normal to cervical cancer by PCR, a sequencing method and bioinformatics programs."
"Phylogenetic analysis based on the whole genome showed that HPV18 samples were more closely related to the European and Asian-American type than the African type. The vaccine strain's L1 nucleotide ( US patent 5820870) showed a close relationship to the...
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Source: Vaccine Weekly (2010-05-05)
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