Alcohol Oxidoreductases
Investigators at University of Virginia, Department of Chemistry release new data on alcohol oxidoreductases
Published in Vaccine Weekly, May 12th, 2010
Researchers detail in 'Identification of a 17beta-hydroxysteroid dehydrogenase type 12 pseudogene as the source of a highly restricted BALB/c Meth A tumor rejection peptide,' new data in alcohol oxidoreductases. According to recent research from the United States, "Mass spectrometric analysis identified the peptide recognized by a cytotoxic T lymphocyte (CTL) specific for the chemically induced BALB/c Meth A sarcoma as derived from a 17beta-hydroxysteroid dehydrogenase type 12 (Hsd17b12) pseudogene present in the BALB/c genome, but only expressed in Meth A sarcoma. The sequence of the peptide is TYDKIKTGL and corresponds to Hsd17b12(114-122) with threonine instead of isoleucine at codon...
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Source: Vaccine Weekly (2010-05-12)
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