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Virology

New virology study findings have been reported by researchers at Stanford University, Department of Medicine

Published in Vaccine Weekly, May 12th, 2010

New research, 'Rotavirus differentially infects and polyclonally stimulates human B cells depending on their differentiation state and tissue of origin,' is the subject of a report. "We have shown previously that rotavirus (RV) can infect murine intestinal B220(+) cells in vivo (M. Fenaux, M. A. Cuadras, N. Feng, M. Jaimes, and H. B. Greenberg, J. Virol. 80:5219-5232, 2006) and human blood B cells in vitro (M. C. Mesa, L. S. Rodriguez, M. A. Franco, and J. Angel, Virology 366:174-184, 2007)," scientists in the United States report.

"However, the effect of RV on B cells, especially those present in the human intestine, the primary site of RV infection, is unknown. Here,...

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