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Biological Products

Reports from National Institute for Medical Research advance knowledge in biological products

Published in Vaccine Weekly, May 26th, 2010

Researchers detail in '1H, 13C and 15N assignment of the C-terminal domain of GNA2132 from Neisseria meningitidis,' new data in biological products. "GNA2132 (Genome-derived Neisseria Antigen 2132) is a surface-exposed lipoprotein discovered by reverse vaccinology and expressed by genetically diverse Neisseria meningitidis strains (Pizza et al. 2000). The protein induces bactericidal antibodies against most strains of Meningococccus and has been included in a multivalent recombinant vaccine against N. meningitidis serogroup B," investigators in London, the United Kingdom report.

"Structure determination of GNA2132 is important for understanding the...

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